|
 |
|
| Composition w/v |
|
| Tobramycin (as sulphate) |
U.S.P 0.3% |
| Fluorometholone |
U.S.P. 0.1% |
| Benzalkonium Chloride Solution |
I.P 0.02% w\v |
| Equivalent to Benzalkonium Chloride |
0.01% |
| (As preservative) |
|
| Sterile Aqueous Base |
q.s. |
|
|
| Dosage form |
| Ophthalmic Suspension (Eye Drops) |
|
| Category |
| Antibiotic + Steriod |
|
|
|
| Description |
Tobramycin is a water-soluble aminoglycoside antibiotic active against a wide variety of gram-negative and gram-positive ophthalmic pathogens. Tobramycin is a drug of choice in corneal ulcers & in pseudomonas infections. Tobramycin inhibits the protein synthesis of bacterias.
Fluorometholone is a steroid reduces inflammation by inhibiting the inflammatory mediators without any side effects. |
|
| Indications |
Nebracin F Drops is indicated for steroid responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists.
The use of a combination drug with an anti infective component is indicated where the risk of superficial ocular infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye. |
|
| Dosage |
| Post operative- one to two drops 6 to 8 times a day. Frequency must be decreased gradually or warranted by improvement in clinical signs. Care should be taken not to discontinue the therapy prematurely. |
|
| Contraindications |
Epithelial herpes simplex keratitis ( dendritic keratitis ) vaccinia, varicella, and many other viral diseases of the cornea and conjunctiva. Mycobacterial infection of the eye. Fungal diseases of ocular structures. Hypersensitivity to a component of the medication.
|
|
| Adverse Reactions |
The most frequent adverse reactions to topical ocular tobramycin are hypersensitivity and localized ocular toxicity including lid itching and swelling and conjunctival erythema.
|
|
| Storage |
| Store in a cool dry place. Protect from light. |
|
| Presentation |
| NEBRACIN F Eye drops is available in sterile plastic bottle of 5ml. |
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