Moxifloxacin & ketorolac ophthalmic solution

Composition w/v
Ketorolac Tromethamine                                        I.P  5mg
Moxifloxacin Hydrochloride BP                               
eq.to Moxifloxacin                                                 5mg
Benzalkonium Chloride Solution                             IP    0.02% v/v
Sterile Aqueous vehicle q.s

Dosage form
Ophthalmic Solution

Category
Antibiotic + NSAID

Description
Moxifloxacin
The antibacterial action of moxifloxacin results from inhibiton of the topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division.

Ketorolac tromethamine
Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug which, when administered systemically, has demonstrated analgesic, anti-inflammatory, and antipyretic activity. The mechanism of its action is thought to be due to its ability to inhibit prostaglandin biosynthesis

Indications
The use of a combination drug with an anti-infective component is indicated Where the risk of superficial ocular infection is high or where there is an Expectation that potentially dangerous numbers of bacteria will be present in the eye.

Dosage and administration
Instill one drop in the affected eye 3 times a day or as directed by the physician.

Contraindicationsn
Moxifloxacin and Ketorolac ophthalmic solution is contraindicated in patients with a history of hypersensitivity to moxifloxacin, to other quinolones, ketorolac or to any of the components in this medication.

Warnings and precautionsn
Moxifloxacin
Not for injection.
Moxifloxacin solution should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye.

Ketorolac tromethamine There is the potential for cross-sensitivity to acetylsalicylic acid, phenylacetic acid derivatives, and other nonsteroidal anti-inflammatory agents. Therefore, caution should be used when treating individuals who have previously exhibited sensitivities to these drugs.

Pregnancy
Since there are no adequate and well-controlled studies in pregnant women. Occumox KT should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation
Caution should be exercised when Occumox KT is administered to a nursing mother.

Pediatric Use
Not recommended below 3 years of age

Storage
Store in a cool & dark place

Presentation
Occumox KT is available in 5 ml ffs pack.                         << Back