Antioxidant capsules

Composition w/v
Omega 3 fatty acids BP
Providing Eicosapentaenoic acid 180 mg
Docosahexaenoic acid 120 mg
Vitamin A ConcentrateIP (oily form) 5000 IU
Vitamin E Acetate IP 25 IU
Vitamin C IP 100 mcg
Vitamin B6 IP 1.5 mg
Folic acid IP 1.5 mg
Chromium Picolinate USP 100 mcg
Methyl paraben IP & Propyl paraben IP
Used as preservatives
Dosage form
Capsules
Category
Antioxidant
Mechanism of action
Increased TNF-a in the lacrimal gland increases lacrimal gland apoptosis ( programmed cell death). Increased apoptosis contributes to decreased in tear production & increase in tearfilm osmolarity that drives dry eye ocular surface disorder.
EPA & DHA elongated with enzymes produces anti inflammatory prostaglandin E3 (PGE 3) & leukotrienes B5 (LTB 5)
EPA blocks the gene expression of pro inflammatory cytokines tumor necrosis factor alpha (TNF a), interleukin-1a (IL-1a), interleukin-1b (IL-1), proteoglycan degrading enzymes & cyclo oxygenase and thus reduces the imflammation.
Meibomian glands use essential fatty acids to synthesize oil. Omega 3 fatty acids clears & thins the meibomian gland secretions & stimulates tear secretions.
Indications
Lacriguard is indicated for chronic dry eyes.
Dosage
The recommended dose of Lacriguard is one capsule a day.
Storage
Store in a cool dry place. Protect from light.
Presentation
LACRIGUARD is available in a blister pack of 10 capsules. << Back
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