LACRIGUARD  

Antioxidant capsules

Lacriguard Antioxidant

Composition w/v
Omega 3 fatty acids BP
Providing Eicosapentaenoic acid                      180   mg
Docosahexaenoic acid                                    120   mg
Vitamin A ConcentrateIP (oily form)                  5000   IU
Vitamin E Acetate IP                                      25   IU
Vitamin C IP                                                  100   mcg
Vitamin B6 IP                                                1.5   mg
Folic acid IP                                                  1.5   mg
Chromium Picolinate USP                              100  mcg
Methyl paraben IP & Propyl paraben IP                                  
Used as preservatives                                  

Dosage form
Capsules

Category
Antioxidant

Mechanism of action
Increased TNF-a in the lacrimal gland increases lacrimal gland apoptosis ( programmed cell death). Increased apoptosis contributes to decreased in tear production & increase in tearfilm osmolarity that drives dry eye ocular surface disorder.

EPA & DHA elongated with enzymes produces anti inflammatory prostaglandin E3 (PGE 3) & leukotrienes B5 (LTB 5)

EPA blocks the gene expression of pro inflammatory cytokines tumor necrosis factor alpha (TNF a), interleukin-1a (IL-1a), interleukin-1b (IL-1), proteoglycan degrading enzymes & cyclo oxygenase and thus reduces the imflammation.

Meibomian glands use essential fatty acids to synthesize oil. Omega 3 fatty acids clears & thins the meibomian gland secretions & stimulates tear secretions.

Indications
Lacriguard is indicated for chronic dry eyes.

Dosage
The recommended dose of Lacriguard is one capsule a day.

Storage
Store in a cool dry place. Protect from light.

Presentation
LACRIGUARD is available in a blister pack of 10 capsules.                            << Back

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